Meeting Focus
Nanoscale sensor for DNA detection on one hand, and DNA-based functional devices for sensoric applications on the other hand are the two fields covered in this years symposium. While the first theme is motivated by the rising interest in DNA and its analytics, the second is fueled by quite unique properties of DNA such as its stability, the association of two strands in a highly specific manner, the possible coding of this effect using the four bases, ease of synthesis in highly defined length and sequence, and an highly established variety of enzymatic or other procedures for DNA manipulation and characterization. These properties lead to many sensoric approaches that often use techniques known from molecular biology and apply them for various concepts for DNA sensing such as based on Förster resonance energy transfer (FRET), aptamers, or DNAzymes. Both fields, nanosensors for DNA as well as DNA-based nanosensors, share a variety of basic technical and physicochemical basic questions, which can be decisive for a future application. Knowing about the various processes in molecular biology which include DNA and elucidating the respective underlying mechanisms allows for the realization of novel functional elements such as DNA machines for the ultrasensitive detection of a variety of analytes of interest. The symposium attempts therefore to bring both fields together and share so their respective experiences and knowledge but also novel approaches and ideas in a synergetic way.